Dosing the Opioid Epidemic with Medical Marijuana

Commentary, Healthcare & Welfare, Daniel Duarte

Over the last decade, Canada has been among the top three countries with the highest per capita opioid consumption. With three thousand and twenty-three opioid-related deaths in 2016, four thousand one hundred twenty in 2017, and four thousand five hundred and eighty-eight in 2018, the problem appears to be escalating quickly despite numerous federal and provincial initiatives.

The available evidence suggests the most effective course of action is to reduce opioid prescriptions and eventually the supply. One promising alternative Canada is particularly well-suited to explore is medical marijuana as a substitute.

Doctors Addicted to Opioid Prescriptions

A study released on October 4, authored by clinician-scientist at Saint Michael’s Hospital Karim Ladha, has found Canadian and US doctors disproportionately prescribe opioid drugs for patients after minor surgeries. Their rates are seven times higher, for example, than in Sweden. 

Ladha explains: “surgery represents one of the most common reasons why someone is first exposed to opioids.” Therefore, he raises the question of whether they are necessary for post-operative pain management.

Instead, some physicians have begun prescribing medicinal cannabis to treat pain, anxiety, insomnia, and other symptoms. With minimal unwanted side effects, cannabis patients have reported these products provide the same sought-after outcomes as other pain relievers.

Two studies published in JAMA Internal Medicine conducted over the last five years have found that—in the US states where marijuana is legal—opioid prescriptions and deaths from opioid overdoses have decreased. As awareness continues to rise, more opioid patients are turning to cannabis alternatives.

With a similar trend, the Canadian Institute for Health Information reports the quantity of opioid prescriptions in the nation has fallen since 2012. The decline has been particularly significant between 2016 and 2017. Opioids dispensed, measured by the defined daily doses per thousand people, dropped by 10.1 percent in that year. 

Ballooning Recreational Use 

During the same period, however, hospitalization due to opioid poisoning increased by 8 percent in Canada, with an average of 17 confinements per day. The fastest-growing rates of hospitalization are men aged 25–44, with a 30 percent increase between 2016 and 2017.

Fentanyl and other fentanyl-related substances, often used as recreational drugs and sold on the black market, have been a major driver of the crisis, according to the Public Health Agency of Canada. From January to March 2019, 82 percent of opioid-related deaths involved fentanyl, and 74 percent involved one or more types of non-opioid substances. 

The federal government announced in 2017 an investment of $100 million over the next five years to address the opioid epidemic. Under the Canadian Drugs and Substances Strategy (CDSS), officials have identified trends and best practices to address substance abuse. 

Then in July 2019, Health Minister Ginette Petipas Taylor increased the budget by $76.2 million to tackle the illegal supply and consumption in underserved communities. One salient point is that this is not just a big-city problem; many mid-sized Canadian cities and Indigenous groups are also struggling with it. 

Marijuana: Gateway or Exit Drug?

Some researchers have suggested marijuana might be a “gateway drug” to opioids since cannabis use usually precedes other harder substances. However, there is no conclusive evidence of a causal link. It’s a chicken-and-egg conundrum

Those already inclined to drug-taking can start with alcohol and nicotine; two more readily available substances that have the same gateway effect on the human brain. Public Health Ontario argues the transition to harder drugs hinge on environmental variables: childhood experiences, social influences, life expectations, and parental use

In any case, opioids do not need a stepping stone. One has a hard time understating how easily anyone can get hooked on them legally: many addicts have no prior drug abuse and are just in treatment for chronic pain or anxiety. When they can no longer get prescriptions, they turn to illegal alternatives that are often laced with deadly contaminants.

New evidence suggests the opposite may be true about marijuana: it could be an exit drug for opioid addiction. Treatment with the non-psychoactive component of cannabis (CBD) has successfully tackled opioid addiction in patients by regulating fear and anxiety. Organizations such as the High Hopes Foundation in Vancouver are launching cannabis-substitution programs where drug users get free and surveilled access to marijuana products.

Cannabis has been legal in Canada for medicinal purposes since 2001, and one year ago the federal government lifted the ban on its recreational use. This promising industry is just beginning to bloom, but it still struggles with red-tape bottlenecks. 

Production-license issuance is slow in many provincial governments, leading to long-lasting illegality. With a larger competition in the black market, investing in the cannabis industry is still a risk.

Therefore, the Canadian government should support provincial authorities to facilitate licensing procedures. If the right policies incentivize innovation in the cannabis market, it could become a path out of the opioid crisis.